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Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)

Clinicaltrials.gov ID

NCT02628067

Status

Recruiting

Study Type

Interventional, Phase 2

Sponsor

Merck Sharp & Dohme LLC

Start Date

December 17, 2015

Anticipated End Date

October 1, 2026

Study Contact

Merck Contact

Phone Number:1-888-577-8839


Merck Canada Contact

Phone Number: 514-428-8600 / 1-800-567-2594

About the Study

In this study, participants with multiple types of advanced (unresectable and/or metastatic) solid tumors who have progressed on standard of care therapy will be treated with pembrolizumab (MK-3475).

Conditions

  • Advanced Cancer

  • Anal Carcinoma

  • Anal Cancer

  • Biliary Cancer

  • Cholangiocarcinoma

  • Bile Duct Cancer

  • Neuroendocrine Tumor

  • Carcinoid Tumor

  • Endometrial Carcinoma

  • Endometrial Cancer

  • Cervical Carcinoma

  • Cervical Cancer

  • Vulvar Carcinoma

  • Vulvar Cancer

  • Small Cell Lung Carcinoma

  • Small Cell Lung Cancer (SCLC)

  • Mesothelioma

  • Thyroid Carcinoma

  • Thyroid Cancer

  • Salivary Gland Carcinoma

  • Salivary Gland Cancer

  • Salivary Cancer

  • Parotid Gland Cancer

  • Advanced Solid Tumors

  • Colorectal Carcinoma

Inclusion/Exclusion Criteria?

Primary, Secondary, Other Outcome Measures??

Locations in Canada

  • Merck Canada, Kirkland, Quebec, H9H 4M7, Canada

About the Study

In this study, participants with multiple types of advanced (unresectable and/or metastatic) solid tumors who have progressed on standard of care therapy will be treated with pembrolizumab (MK-3475).

Conditions

  • Advanced Cancer

  • Anal Carcinoma

  • Anal Cancer

  • Biliary Cancer

  • Cholangiocarcinoma

  • Bile Duct Cancer

  • Neuroendocrine Tumor

  • Carcinoid Tumor

  • Endometrial Carcinoma

  • Endometrial Cancer

  • Cervical Carcinoma

  • Cervical Cancer

  • Vulvar Carcinoma

  • Vulvar Cancer

  • Small Cell Lung Carcinoma

  • Small Cell Lung Cancer (SCLC)

  • Mesothelioma

  • Thyroid Carcinoma

  • Thyroid Cancer

  • Salivary Gland Carcinoma

  • Salivary Gland Cancer

  • Salivary Cancer

  • Parotid Gland Cancer

  • Advanced Solid Tumors

  • Colorectal Carcinoma

Interventions

BIOLOGICAL:

  • pembrolizumab

Locations in Canada

  • Merck Canada, Kirkland, Quebec, H9H 4M7, Canada

  • Instagram
  • Facebook
  • Twitter
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The Canadian Cholangiocarcinoma Collaborative (C3) is supported by a Canadian Cancer Society Breakthrough Team Grant in partnership with the Canadian Institutes of Health Research. The granting funds for C3 are managed by The Ottawa Hospital Research Institute, which serves as the lead institute for all collaborative operations.

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