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A Study of SGN-B7H4V in Advanced Solid Tumors

Clinicaltrials.gov ID

NCT05194072

Status

Recruiting

Study Type

Interventional, Phase 1

Sponsor

Seagen Inc.

Start Date

January 11, 2022

Anticipated End Date

June 29, 2025

Study Contact

Name: Seagen Trial Information Support

Phone Number: 866-333-7436

Email: clinicaltrials@seagen.com

About the Study

This study will test the safety of a drug called SGN-B7H4V in participants with solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease.

Conditions

  • Ovarian Neoplasms

  • Peritoneal Neoplasms

  • Fallopian Tube Neoplasms

  • Triple Negative Breast Neoplasms

  • HER2 Negative Breast Neoplasms

  • Hormone Receptor Positive Breast Neoplasms

  • Endometrial Neoplasms

  • Carcinoma, Non-Small-Cell Lung

  • Cholangiocarcinoma

  • Gallbladder Carcinoma

  • Adenoid Cystic Carcinoma

Inclusion/Exclusion Criteria?

Primary, Secondary, Other Outcome Measures??

Locations in Canada

  • The Ottawa Hospital, Ottawa, Ontario, K1H 8L6, Canada

About the Study

This study will test the safety of a drug called SGN-B7H4V in participants with solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to the body besides treating the disease.

Conditions

  • Ovarian Neoplasms

  • Peritoneal Neoplasms

  • Fallopian Tube Neoplasms

  • Triple Negative Breast Neoplasms

  • HER2 Negative Breast Neoplasms

  • Hormone Receptor Positive Breast Neoplasms

  • Endometrial Neoplasms

  • Carcinoma, Non-Small-Cell Lung

  • Cholangiocarcinoma

  • Gallbladder Carcinoma

  • Adenoid Cystic Carcinoma

Interventions

DRUG:

  • SGN-B7H4V

Locations in Canada

  • The Ottawa Hospital, Ottawa, Ontario, K1H 8L6, Canada

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The Canadian Cholangiocarcinoma Collaborative (C3) is supported by a Canadian Cancer Society Breakthrough Team Grant in partnership with the Canadian Institutes of Health Research. The granting funds for C3 are managed by The Ottawa Hospital Research Institute, which serves as the lead institute for all collaborative operations.

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